Follow the given steps to disable windows hotkeys combinations:
To use this feature, you will need to be logged into your computer with administrative rights.
Click Start button and type regedit in Run option then press Enter for next.
Here locate the location to:
HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Policies\Explorer
Here in right side panel, right click to create a new DWORD value with the name NoWinKeys
(it is case sensitive) or modify the existing value called NoWinKeys values and assign number 1 in value data box.
Now close the registry editor and restart your computer after any changes to go into effect.
But next time, if you want to enable windows hotkeys combinations then simply change the value of data box or delete the NoWinKeys DWORD item.